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Table 2 Summary of conflict-related health research studies inside Syria, January 2011–December 2019

From: Conflict-related health research in Syria, 2011–2019: a scoping review for The Lancet - AUB Commission on Syria

First author (Publication year)

First & Last (Senior) authors’ country of institutional affiliation

Type of institutional affiliation

Description

Theme (Subtheme)

Study Period (month/year)

Methodology

Study Population

Geographic focus

Funding

Alasaad (2013) [8]

First: Syria, Switzerland, Spain

Last: N/A

First: academic

Reviews YouTube and social media videos to describe leishmaniasis outbreaks in Deir ez-Zor.

Health status

January–March 2013

YouTube and Facebook video review, contact with local communities

General population

Deir ez-Zor

Not reported

Ahmad (2014) [9]

First: UK

Last: N/A

First: academic

Assesses the influences of neighborhood socioeconomic position and urban informal settlements on women’s health.

Health determinants and risks

April–May 2011

Key informant interviews, unstructured observations

Professionals working with populations in informal communities; women in informal settlements

Aleppo

Institute of Health and Society, Newcastle University, UK

Hoetjes (2014) [10]

First: Netherlands

Last: Netherlands

First: humanitarian

Last: humanitarian

Documents results of a screening program and examines food security and factors affecting nutritional status amongst the Tal-Abyad population (Al-Raqqa), and describes MSF nutrition programs.

Health status; humanitarian assistance, response or needs

2013

Mixed methods (middle-upper arm circumference screening; qualitative survey)

IDPs living in schools

Al-Raqqa

Not reported

Rosman (2014) [11]

First: Israel

Last: Israel

First: academic/ military

Last: academic/ military

Reports on physician reviews of YouTube videos documenting a sarin attack to determine clinical presentation and review the management of a mass casualty event

War strategies / alleged IHL violations

August–September 2013

Physician review of YouTube videos

Casualties of Ghouta sarin attack

Damascus

Not reported

Alshiekhly (2015) [12]

First: Syria

Last: Syria

First: academic

Last: academic

Evaluates feasibility of Facebook as a teaching modality for a course on medical emergencies in dental practice

Health system (workforce)

March–April 2014

Pre and post questionnaire

Dental students

Not reported

None

Doocy (2015) [13]

First: USA

Last: Belgium

First: academic

Last: academic

Documents humanitarian needs and priorities among households in need of assistance in accessible communities

Humanitarian assistance, response or needs

April–June 2014

Needs assessment

General population

Predominantly government-controlled areas (Aleppo, As-Sweida, Damascus, Dara’a, Al-Hasakeh, Homs, Lattakia, Rural Damascus, Tartous)

Humanitarian assistance programs

Doocy (2015) [14]

First: USA

Last: USA

First: academic

Last: academic

Describes trends in internal displacement and analyzes the association between displacement and household well-being and humanitarian needs.

Humanitarian assistance, response or needs

March 2011–June 2014

Review of published IDP estimates; needs assessment

General population

National

Not reported

Guha-Sapir (2015) [15]

First: Belgium

Last: Lebanon

First: academic

Last: academic

Documents direct conflict-related deaths of women and children using VDC data.

Mortality; war strategies / alleged IHL violations

March 2011–January 2015

VDC data analysis

Civilians

National

emBRACE—Building resilience amongst communities in Europe & Chatham House

Price (2015) [16]

First: USA

Last: USA

First: humanitarian

Last: humanitarian

Applies capture - recapture methods to data from four sources to estimate mortality, and describes the issues associated with accurately documenting mortality estimates in conflict settings

Mortality

December 2012–March 2013

Multiple systems estimation / capture -recapture

Civilians and combatants

Homs, Hama

Not reported

Sekkarie (2015) [17]

First: USA

Last: USA

First: clinical

Last: academic

Explores the impact of conflict on dialysis services

Health system (service provision, workforce)

2013

Key informant Interviews

Dialysis facility administrators, providers and patients

Non-government-controlled areas (Aleppo, Homs, Idlib)

Not reported

Tajaldin (2015) [18]

First: USA

Last: USA

First: academic

Last: academic

Compares polio case rates using laboratory versus clinical case definitions and different surveillance systems

Health system (information systems); health status

2013–2014

Analysis of EWARS and EWARN data

General population

National

Not reported

Trelles (2015) [19]

First: Belgium

Last: Belgium

First: humanitarian

Last: humanitarian

Reports on surgical cases and intraoperative mortality rates at an MSF field hospital

Humanitarian assistance, response or needs

September 2012–January 2014

Analysis of MSF programme data

Surgical patients

Jabal Al Akrad, Latakia Northwest Syria

Médecins Sans Frontières-Operational Centre, Belgium.

Charlson (2016) [20]

First: Australia, USA

Last: Australia, USA

First: academic

Last: academic

Estimates prevalence of depression and PTSD and models likely current and future mental health service requirements

Health status; Health system (service provision, workforce)

Global Burden of Disease Study 2010, modelling for period 2015–2030

Global Burden of Disease (GBD) methodology and modelling

General population

National

Queensland Department of Health, Australia

El-Khani (2016) [21]

First: UK

Last: UK

First: academic

Last: academic

Examines feasibility of the “bread wrapper approach” which involves distribution of psychological support information on leaflets inserted into bread wraps and using the bread wraps to circulate questionnaires assessing the usefulness of the information provided.

Humanitarian assistance, response or needs

Not reported

Questionnaire

General population

Northern Syria next to the borders with Turkey

The University of Manchester’s ESRC Transformative Research Prize Committee

Elsafti (2016) [22]

First: Qatar, Egypt

Last: Belgium

First: clinical

Last: academic

Documents the family, educational, and health status of Syrian children and associated humanitarian needs

Health status; humanitarian assistance, response or needs

May 2015

Needs assessment

Children less than 15 years old

Aleppo, Hama, Idlib, Lattakia

None

Ismail (2016) [23]

First: UK

Last: Lebanon

First: academic

Last: academic

Describes trends in tuberculosis, measles and polio case numbers in Syria and challenges of disease surveillance in the conflict context.

Health system (information systems); health status

Peer-reviewed analysis (2005–2015), EWARN & EWARS analysis (2014–2015)

Analysis of EWARN, EWARS data

General population

National

Not reported

Jefee-Bahloul (2016) [24]

First: USA

Last: USA

First: academic

Last: academic

Examines attitudes of Syrian healthcare providers towards Store & Forward tele-mental health consultations

Health system (service provision)

Not reported

Online survey

Syrian health-care professionals affiliated with humanitarian NGOs

Aleppo, Damascus, Idlib, Othersa

Not reported

Mowafi (2016) [25]

First: USA

Last: France

First: academic

Last: humanitarian

Assesses the functional status and capacity of trauma hospitals

Health system (service provision, workforce)

February–March 2015

Survey

Hospitals providing secondary or tertiary surgical care in non-government-controlled areas

Aleppo, Damascus (non-government-controlled area), Dara’a, Hama, Homs, Idlib, Lattakia, Quneitra, Rural Damascus

Yale University & UOSSM.

Sparrow (2016) [26]

First: USA

Last: Australia

First: academic

Last: academic

Compares two infectious disease surveillance systems, the Ministry of Health-run EWARS system and the independent, non-governmental EWARN

Health system (information system); health status

2014–2015

Analysis of EWARS and EWARN data

General population

National

Not reported

Al-Saadi (2017) [27]

First: Syria

Last: Syria

First: academic

Last: academic

Reports prevalence and risk factors of psychological distress among medical students in Damascus

Health status; Health system (workforce)

November 2015

Online questionnaire

Second to sixth-year medical students at Damascus University

Damascus

None

Alsaied (2017) [28]

First: USA

Last: Canada, Qatar

First: clinical

Last: academic, clinical

Reports on the operations of UOSSMb primary care clinics in Opposition Territories and reasons for consultations

Humanitarian assistance, response or needs; health status

January 2014–December 2015

Retrospective administrative database review

Patients seen at 10 primary care centers

Opposition-controlled areas (Aleppo, Deir ez-Zor, Hama, Homs, Idlib, Lattakia)

None

Arafat (2017) [29]

First: Syria

Last: Syria

First: clinical

Last: academic

Describes differences in patterns of injury and mortality rates among patients with penetrating abdominal injuries at Damascus Hospital

Health status

October 2012–June 2013

Retrospective review of records

Patients with penetrating abdominal injuries

Damascus

None

Baaity (2017) [30]

First: Syria

Last: Syria

First: academic

Last: academic

Reports the prevalence of extended spectrum β lactamases of E. coli in isolates from patients in Al-Assad Teaching Hospital, Lattakia

Health status

October 2014–November 2016

Analysis of data regarding clinical isolates

Patients in Al-Assad teaching hospital

Lattakia

Not reported

Cummins (2017) [31]

First: Not stated

Last: Turkey

First: humanitarian

Last: humanitarian

Aims to understand the impact of providing food kits in Idlib and how it disturbs the food market, and proposes market-based approach as an alternative for food aid provision.

Humanitarian assistance, response or needs

2016

Interviews

Community members in Idlib (Darkoush and Salquin)

Idlib

UK Department for International Development (DFID) through the Urban Crises Learning Fund.

Diggle (2017) [32]

First: UK

Last: UK

First: humanitarian

Last: academic

Reflects on operational experiences and analyses humanitarian health response data collected in contested and opposition-held areas of Syria

Mortality; health status; humanitarian assistance, response or needs

2013–2014

Analysis and review of data from multiple operational databases

Civilians & combatants

Contested and opposition-controlled areas (governorates not specified)

None

Doocy (2017) [33]

First: USA

Last: USA

First: academic

Last: academic

Identifies humanitarian needs and priorities among displaced and female headed households in government-controlled areas

Humanitarian assistance, response or needs

April–June 2016

Needs assessment

Displaced & female headed households

Government-controlled areas (Aleppo, As-Sweida, Damascus, Dara’a, Hama, Al-Hasakeh, Homs, Lattakia, Rural Damascus, Tartous)

US-based international nongovernmental organization

Doocy (2017) [34]

First: USA

Last: Turkey

First: academic

Last: humanitarian

Examines the effectiveness of three assistance programs (in-kind food commodities, food vouchers, unrestricted vouchers) in improving food security in northern Syria.

Humanitarian assistance, response or needs; Health determinants and risks

September–December 2014, May/June 2015

Serial household surveys, shopkeeper survey and analysis of program monitoring data

Beneficiary households; shopkeepers participating in the voucher program

Idlib

GOAL

Elamein (2017) [35]

First: Turkey

Last: Turkey, Egypt

First: UN agency

Last: UN agency, academic

Describes the first operational use of the Monitoring Violence against Health Care (MVH) tool to report real-time incident data for attacks on healthcare infrastructure, workers and patients

War strategies / alleged IHL violations; health system (service provision; workforce)

November 2015–December 2016

Analysis of MVH data

Healthcare workers, health service users

Aleppo, Al-Raqqa, Damascus, Dara’a, Deir ez-Zor, Hama, Homs, Idlib, Lattakia, Quneitra, Rural Damascus

None

Fouad (2017) [36]

First: Lebanon

Last: Lebanon

First: academic

Last: academic

Reports on attacks on healthcare and experiences of health workers inside Syria

War strategies / alleged IHL violations; health system (workforce; service provision)

Not reported

Mixed methods study (quantitative data analysis, consultations, testimonials)

Health workers

National

IDRC; American University of Beirut

Fujita (2017) [37]

First: Japan

Last: Sweden

First: academic

Last: academic

Presents daily time series analysis of violent deaths in Syria, including temporal and spatial analysis, and compares trends with those of violent and non-violent deaths in the non-conflict context of England

Mortality

1200-day period commencing 500 days post conflict onset

Secondary analysis and modelling of Violations Documentation Center data

Civilians and military personnel

Aleppo, Damascus, Dara’a, Homs, Idlib

Bilateral Joint Research Project between JSPS, Japan, and FRS-FNRS, Belgium. Grants-in-Aid for Scientific Research from MEXT Japan

Hawat (2017) [38]

First: Syria

Last: Syria

First: academic

Last: academic

Reviews the epidemiology of cutaneous and visceral leishmaniasis in Lattakia and examines the effects of the Syrian conflict on incidence

Health status

2006–2016

Analysis of Leishmaniasis and Contagious Diseases Centre data for new cases of leishmaniasis

General population

Lattakia

Not reported

Mohammad (2017) [39]

First: Syria

Last: Canada

First: academic

Last: clinical, academic

Assesses asthma prevalence, asthma control and quality of life among those with diagnosed asthma;

Among non-asthmatics, estimates prevalence of respiratory symptoms, PTSD symptoms and other chronic disease co-morbidities.

Health status

Not reported

Cross-sectional survey

IDPs in Al-Herjalleh shelter aged > = 5 years

Damascus

Syrian Private University

Sahloul (2017) [40]

First: USA

Last: USA

First: academic

Last: clinical

Examines quality of cancer care and needs in government-controlled areas versus besieged areas, and provision of care in general clinics compared with specialized cancer care clinics.

Health system (service provision, workforce); war strategies / alleged IHL violations

Not reported

Cross-sectional survey

Oncologists and surgeons working in cancer clinics, and general physicians

Government-controlled areas (Damascus, Lattakia, Homs, and West Aleppo) and besieged areas (East Ghouta, East Aleppo, and Idlib)

Not reported

van Berlaer (2017) [41]

First: Belgium

Last: Belgium

First: academic

Last: academic

Documents diagnoses, injuries and comorbidities in children in Northern Syria

Health status; humanitarian assistance, response or needs

May 2015

Cross-sectional household survey

Children younger than 15 years

Aleppo, Hama, Idlib, Lattakia

None

Abbas (2018) [42]

First: Syria

Last: Syria

First: academic

Last: academic

Examines efficacy and feasibility of peer- led versus professional-led training in basic life support course for medical students

Health system (workforce)

April 2016

Randomized controlled trial

Medical students in pre-clinical years at Syrian Private University

Damascus

None

Albaroudi (2018) [43]

First: Syria

Last: Syria

First: academic

Last: academic

Examines prevalence of iron deficiency and iron deficiency anemia in children and socioeconomic associations, and effectiveness of oral iron supplements

Health status; health determinants and risks

1) Retrospective part: November 2011–November 2015

2) Prospective part: 2 month period, not specified

Retrospective medical record review; parental questionnaire & clinical data analysis

Children seen at primary care clinics at the Children’s Hospital in Damascus

Damascus

Damascus University

Ballouk (2018) [44]

First: Syria

Last: Syria

First: academic

Last: academic, government

Assesses gingival health status in children aged 8–12 years in Damascus city

Health status

September 2016–January 2017

Cross-sectional, school-based oral health survey

Children aged 8–12 years

Damascus

None

Chen (2018) [45]

First: USA

Last: USA

First: academic

Last: academic

Estimates the number of unique identifiable deaths in the Syrian conflict by deduplicating four datasets

Mortality; war strategies and alleged IHL violations

March 2011–April 2014

Unique entity estimation using mortality data from VDC, SNHR, CSR-SY, SSc

Civilians and combatants

Not reported

National Science Foundation (NSF), Amazon Research Award, Laboratory for Analytic Sciences (LAS).

Darwish (2018) [46]

First: Syria

Last: Syria

First: academic

Last: academic

Reviews pediatric chest injuries treated in the Mouassat University Hospital in Damascus before and during the Syrian crisis

Health status

January 2005–December 2016

Hospital record review

Pediatric chest trauma patients

Damascus

None

de Lima Pereira (2018) [47]

First: Syria

Last: Netherlands

First: humanitarian

Last: humanitarian

Assesses vaccine-preventable disease risk and vaccination needs, and vaccination coverage following an immunization program

Humanitarian assistance, response or needs; health status

June–September 2015

Cross-sectional household survey

Children < 5 years old

Aleppo

None

Doocy (2018) [48]

First: USA

Last: USA

First: academic

Last: academic

Assesses humanitarian needs in government-controlled areas of Syria

Humanitarian assistance, response or needs

April – June 2016

Needs assessment

General population

Government-controlled areas (Aleppo, As-Sweida, Damascus, Dara’a, Hama, Al-Hasakeh, Homs, Lattakia, Rural Damascus, Tartous)

US-based international nongovernmental organization

Footer (2018) [49]

First: USA

Last: USA

First: academic

Last: academic

Explores the impact of the Syrian conflict on health workers and healthcare in opposition-controlled areas and challenges faced, including in responding to chemical weapons attacks

Health system (service provision, workforce); war strategies / alleged IHL violation

October 2014 (Gaziantep), July–August 2017 (online)

Semi-structured interviews

Health-care professionals with experience in opposition-controlled areas of Syria

Opposition- controlled areas (governorates not specified)

MacArthur Foundation

Garry (2018) [50]

First: UK

Last: UK

First: academic

Last: academic

Explores factors impacting provision of healthcare for NCDs in opposition-controlled Syria

Humanitarian assistance, response or needs

June–August 2017

Semi-structured interviews

Humanitarian healthcare staff or Syrian health workers from opposition-controlled / contested areas

Opposition-controlled areas (governorates not specified)

UK Research and Innovation (Global Challenges Research Fund)

Guha-Sapir (2018) [51]

First: Belgium

Last: USA

First: academic

Last: academic

Reports demographic, spatial, and temporal patterns of direct deaths among civilians and opposition combatants using VDC data

Mortality; war strategies / alleged IHL violations

March 2011–December 2016

VDC data analysis

Civilians and combatants

Non-government-controlled areas (governorates not specified)

None

Haar (2018) [52]

First: USA

Last: USA

First: academic

Last: academic

Describes a standardized field survey tool for documenting attacks on healthcare, and compares this dataset to PHR’s database that uses open sources to track attacks on health facilities

War strategies / alleged IHL violations; health system (service provision, workforce)

2016

Development of prospective surveillance methodology, standardized reporting questionnaire

NA

Aleppo, Hama, Homs, Idlib

MacArthur Foundation, the Oak Foundation, Berkeley Research Impact Initiative

Idris (2018) [53]

First: Syria

Last: Syria

First: academic

Last: academic

Reports prevalence of cigarette smoking among university students and examines the impact of war on smoking behavior

Health determinants and risks

May 2015

Online cross-sectional survey

Undergraduate students at Damascus University.

Damascus

None

Khamis (2018) [54]

First: Syria

Last: Lebanon

First: government

Last: academic

Reports National AIDS Program data and examines how the war affected HIV surveillance and voluntary counselling and testing

Health status; health system (service provision)

2010–2016

Secondary analysis of National AIDS Program surveillance data

General population

National

Not reported

Kubitary (2018) [55]

First: Syria

Last: Syria, France

First: academic

Last: academic

Examines validity of the Arabic version of the two-question Quick Inventory of Depression (QID-2-Ar) in Syrian multiple sclerosis patients.

Health status

Not reported

Cross-sectional study

Multiple sclerosis patients aged 18–60 years seen at two hospitals

Damascus

None

Kubitary (2018) [56]

First: Syria

Last: France, Syria

First: academic

Last: academic

Examines the effects of Therapy by Repeating Phrases of Positive Thoughts (TRPPT) on PTSD, Sleep Disorder and War Experiences among school children and adolescents

Health systems (service provision); health status

Not reported

Clinical trial

Children & adolescents aged 13–17 years

Damascus

Not reported

Meiqari (2018) [57]

First: Netherlands

Last: Netherlands

First: humanitarian, academic

Last: humanitarian

Describes the impact of the war on child health in Tal Al-Abyad and Kobane, using available medical and humanitarian data from Médecins Sans Frontières

Health status; humanitarian assessment, response or needs

April 2013–September 2016

Analysis of MSF clinical data and reports

Children < 5 years old who attended an MSF facility

Aleppo, Al-Raqqa

Not reported

Morrison (2018) [58]

First: UK

Last: N/A

First: academic

Reports the experiences and challenges of health service delivery under siege

Health system (service provision); war strategies / alleged IHL violations

Mid-2016

Interviews and focus group discussions

Interim Council and healthcare professionals in four besieged urban areas

Opposition-controlled areas (Aleppo, Damascus)

DFID’s Urban Crises Programme

Othman (2018) [59]

First: Not stated

Last: Australia

First: independent

Last: academic

Evaluates the impact of a six-month programme to address organizational stressors and promote staff-care and social support

Health determinants and risks; health system (workforce)

Not reported

Evaluation research/ Implementation research

Staff working for a psychosocial support organization

Non-government-controlled areas (Idlib)

Not reported

Perkins (2018) [60]

First: UK

Last: Syria

First: academic

Last: academic

Reports the incidence of psychological symptoms among school-aged children in Damascus and Lattakia

Health status

Not reported

Cross-sectional study

School children (8–15 years old)

Damascus, Lattakia

Not reported

Rehman (2018) [61]

First: Austria

Last: Germany; Austria

First: academic

Last: academic, clinical

Describes the leishmaniasis surveillance control program

Health status

November 2014–

February 2016

Molecular–epidemiologic survey of cutaneous leishmaniasis in sentinel sites

General population (including IDPs)

Northern Syria (Aleppo, Idlib, Hama, Al-Raqqa, and Al-Hasakeh)

USAID & DFID

Rodriguez-Llanes (2018) [62]

First: Belgium

Last: USA

First: academic

Last: academic

Reports demographic characteristics of victims of chemical weapons attacks

War strategies / alleged IHL violations; mortality

March 2011–April 2017

VDC data analysis

Deceased victims of chemical weapons attacks

Non-government-controlled areas (Aleppo, Damascus, Hama, Idlib)

None

Sawaf (2018) [63]

First: Syria

Last: Syria

First: academic

Last: academic

Explores medical students’ attitudes and factors affecting their specialty choices and career plans

Health system (workforce)

August 2016

Self- administered questionnaire

Medical students at three universities in Damascus

Damascus

Syrian Private University

Sikder (2018) [64]

First: USA

Last: Jordan

First: academic

Last: independent

Assesses the effectiveness of a multilevel risk reduction intervention in maintaining Free Chlorine Residual in household drinking water

Humanitarian assessment, response or needs

January 2018

Cross-sectional study using interviews & observations; water quality testing

Chlorination station operators, well owners, households, Methology

Opposition-controlled areas in southern Syria (governorates not specified)

WoS (Amman hub) WASH Sector, UNICEF, UNICEF/NYC and Tufts University

Sikder (2018) [65]

First: USA

Last: Jordan

First: academic

Last: UN agency

Examines WASH access and needs in opposition controlled southern Syria

Humanitarian assessment, response or needs

June/July 2016–February 2017

Cross-sectional household surveys & water quality testing

Households

Opposition-controlled areas (Dara’a, Quneitra)

WoS (Amman hub) WASH Sector

Turk (2018) [66]

First: Syria

Last: USA

First: academic

Last: academic

Assesses medical students attitudes toward research

Health system (workforce)

Not reported

Self-administered questionnaire

Medical students at University of Damascus

Damascus

None

Wong (2018) [67]

First: USA

Last: USA

First: academic

Last: clinical

Reviews attacks on ambulances

War strategies / alleged IHL violations; health system (service provision)

January 2016–December 2017

Secondary data analysis on individual attacks reported by SNHR

NA

National

None

Ahmad (2019) [68]

First: UK

Last: UK

First: academic

Last: academic

Examines perceptions of married women living in low-income formal and informal neighborhoods in Aleppo on the effects of neighbourhood on their health and well-being

Health determinants and risks

April–June 2011

Semi-structured interviews

Married women living in informal and low-income formal neighbourhoods

Aleppo

European Commission FP7 programme grants MedCHAMPS and RESCAP-MED

Abu Salem (2019) [69]

First: Lebanon

Last: Lebanon

First: academic

Last: academic

Uses VDC data to confirm conflict events and identify fake news in FA-KES, a fake news dataset

Mortality

Not reported

Analysis of news articles and reports on incidence of deaths compared to VDC dataset

General population

National

American University of Beirut

Alaryan (2019) [70]

First: Syria

Last: Syria

First: academic

Last: academic

Reports on prescription drug misuse in Damascus and Damascus countryside during the conflict

Health system (medical products)

December 2016–March 2017

Cross-sectional survey

Community pharmacists

Damascus and Rural Damascus

Not reported

Alhaffar (2019) [71]

First: Syria

Last: Syria

First: academic

Last: clinical

Examines prevalence of burnout syndrome among resident physicians in training

Health system (workforce)

July 2018

Online questionnaire

Resident physicians in training from 12 hospitals in 8 governorates who spent at least one year in a residency program approved by the Syrian Commission of the Medical Specialties.

Damascus, Aleppo, Lattakia, Tartous, Dara’a, Rural Damascus, Hama, Homs

Not funded (self-funded)

Alhaffar (2019) [72]

First: Syria

Last: Syria

First: academic

Last: academic

Examines the prevalence of caries and oral health status among school children in Damascus, and associations with socio-economic status

Health status; Health determinants and risks

September–November 2017

School-based survey (questionnaire and clinical examination)

Seventh-grade school children in 10 randomly selected schools covering Damascus city

Damascus

Not funded (self-funded)

Alhammoud (2019) [73]

First: Qatar

Last: UK

First: clinical

Last: clinical

Reports the experience of one field hospital in Aleppo providing treatment of open shaft fractures

Health system (service provision)

July 2011–July 2016

Retrospective medical record review

Patients with open long bone fractures managed with external fixation

Aleppo

Not reported

Alothman (2019) [74]

First: Syria

Last: India

First: academic

Last: academic

Reports on war injury presentations to Hama National Hospital

Health system (service provision)

2017

Retrospective medical record review

War injured patients received by Hama National Hospital

Hama

Not reported

Ballouk (2019) [75]

First: Syria

Last: Syria

First: academic

Last: academic, government

Examines prevalence of dental caries among school-aged children in Damascus city

Health status

September 2016–January 2017.

School based oral health survey (clinical examination)

School children aged 8–12 years and resident in Damascus city during the study period

Damascus

Not funded (self-funded)d

Blackwell (2019) [76]

First: USA

Last: not stated

First: humanitarian

Last: humanitarian

Examines the impact of a cash-based assistance program on women’s empowerment and violence against women

Humanitarian assessment, response or needs; health status

March–August 2018

Semi-structured interviews

Woman aged 18–59 who received a cash payment over a three-month period

Al-Raqqa

UK Department for International Development (DFID)

Douedari (2019) [77]

First: UK

Last: UK

First: academic

Last: academic

Examines perceptions of local health providers and service users regarding health system governance, roles and relationships of institutional actors, and challenges and potential solutions

Health system (governance)

July–August 2016

Key informant interviews

Health system providers from health directorates, humanitarian NGOs, donors, and service-users

Opposition-controlled provinces (Aleppo, Dara’a, Hama, Idlib, Rural Damascus)

Chevening Scholarships

Duclos (2019) [78]

First: UK

Last: UK

First: academic

Last: academic

Examines cross-border humanitarian assistance and the challenges encountered by humanitarian health actors delivering health care in North-West Syria (Turkish border)

Humanitarian assessment, response or needs; health system (service provision)

September 2017

Mixed methods, including key informant interviews, desk reviews and expert consultations

Humanitarian aid professionals in Turkey-based organizations operating in North-West Syria, WHO-Turkey staff members and members of Syrian health directorates.

North-West Syria

London School of Hygiene and Tropical Medicine, Department of Infectious Disease Epidemiology, and the International Development Research Center (IDRC)

Falb (2019) [79]

First: USA

Last: USA

First: humanitarian

Last: humanitarian

Examines associations between depressive symptoms and their potential risk factors (including stressors, intimate partner violence)

Health status; health determinants and risks

March–April 2018

Cross-sectional survey

Married women who participated in a cash transfer program

Al-Raqqa

UK Department for International Development (DFID)

Fardousi (2019) [80]

First: Lebanon, UK

Last: UK, Singapore

First: academic

Last: academic

Examines perspectives of healthcare workers on issues of safety, resource management and handling of mass casualties during siege

Health system (workforce, service provision); war strategies / alleged IHL violations

Not stated

Key informant interviews

Syrian healthcare workers and service users who experienced siege in Aleppo in 2016 or Ghouta (Rural Damascus) in 2013–2017

Aleppo, Rural Damascus

Chevening Scholarships

Fradejas-Garcia (2019) [81]

First: Spain

Last: N/A

First: academic

Explores experiences of remote cross-border operations

Humanitarian assessment, response or needs

Not reported

Ethnographic study through interviews

Aid workers and organizations – UN agencies, international NGOs and Syrian NGOs – providing relief assistance to Syria remotely

Turkish border city of Gaziantep

Not reported

Hallak (2019) [82]

First: Turkey

Last: Turkey

First: academic

Last: academic

Examines optimal shelter locations for IDPs

Humanitarian assessment, response or needs

December 2017–February 2018

Needs assessment using focus group discussions, key informant interviews and questionnaire with direct beneficiaries; mathematical modelling

Direct beneficiaries in 26 sub-districts within Idlib

Idlib

Not reported

Hamid (2019) [83]

First: Syria

Last: Syria

First: academic

Last: academic

Compares dental and gingival status among children with and without PTSD

Health status

Not reported

Case control study

Children (9–14 years old) who attended psychiatry department (cases) or dental service (controls)

Damascus

Damascus University

Hamzeh (2019) [84]

First: Syria

Last: Syria

First:, academic

Last: academic

Assesses knowledge and awareness of diabetes mellitus and its complications and effects of the conflict on care-seeking behavior among diabetes patients in Damascus

Health status; health determinants and risks

August–November 2017

Questionnaire

Diabetes mellitus patients attending clinics at the four main hospitals in Damascus

Damascus

Not funded

Jamal (2019) [85]e

First: UK

Last: Lebanon

First: academic

Last: academic

Examines the UNRWA health system and factors contributing to its resilience and enabling ongoing delivery of services to Palestinian refugees inside Syria during the crisis

Health system (service provision, governance, medical products, workforce)

February–August 2017

Key informant interviews, group model building sessions

UNRWA clinical and administrative professionals engaged in health service delivery for Palestinian refugees in Syria over the course of the conflict

Damascus, Jaramana (Rural Damascus), City Center Polyclinicf and Aleppo

Wellcome Trust

Mic (2019) [86]

First: Turkey

Last: Turkey

First: academic

Last: academic

Examines optimal locations for primary health care centers in Idlib to allow services to the greatest number of people

Humanitarian assessment, response or needs

March–May 2018

Needs assessment using focus group discussions, key informant interviews and questionnaire with direct beneficiaries; mathematical modelling

Direct beneficiaries in 23 sub-districts within Idlib

Idlib

Çukurova University (Adana, Turkey)

Mohammad (2019) [87]

First: Syria

Last: USA

First: academic

Last: academic

Evaluates effectiveness of personalized supervision of residents on improving prescribing for asthma management, and effectiveness of mobile video training for inhaler technique

Health system (service provision)

April–May 2018

Clinical audits; evaluation of efficacy of video-mobile education

Asthma patients at internal medicine clinic in public hospital in Damascus

Damascus

Not reported

Muhjazi (2019) [88]

First: Egypt

Last: UK

First: UN agency

Last: humanitarian

Reports cutaneous leishmaniasis epidemiology over the course of the war

Health status; Health system (information system)

2007–2010, 2011–2018

Secondary data analysis of 1) MOH routine surveillance system, 2) EWARS, 3) MENTOR Initiative data

General population

National

Not funded

Okeeffe (2019) [89]

First: Syria

Last: Netherlands

First: humanitarian

Last: humanitarian

Describes blast-wound cases admitted to an MSF supported district hospital during the Raqqa military offensive and the first months of the post offensive period.

Health status; Health system (service provision); humanitarian assessment, response, and needs

June 2017–March 2018

Retrospective chart review

New blast-wound injured cases admitted to MSF-district hospital in Al-Raqqa in the offensive (June–October 2017) or post offensive period (October 2017–March 2018)

Al-Raqqa

Not funded

Ri (2019) [90]

First: USA

Last: USA

First: academic

Last: academic

Compares trends of attacks on healthcare and civilian casualites to assess feasibility of using publicly available data on attacks on healthcare facilities to describe population-level violence

Mortality; War strategies / alleged IHL violations

March 2011–November 2017

Secondary analysis of publicly available data from: VDC (civilian casualties), PHR (attacks on healthcare facilities), UNHCR (registered Syrian refugees)

Civilians

National

Not funded

Roumieh (2019) [91]

First: Syria

Last: Syria

First: academic

Last: academic

Assesses prevalence of postpartum depression among Syrian women in Damascus and examines associated risk factors

Health status; Health determinants and risks

January–December 2017

Cross-sectional questionnaire

Postpartum women attending 8 primary healthcare centers in Damascus

Damascus

Damascus University

Terkawi (2019) [92]

First: USA, Saudi Arabia

Last: Saudi Arabia

First: humanitarian, academic, clinical, thinktank/ research organization

Last: academic

Assesses disease burden and clinical presentations of children and adolescents attending a healthcare center in Atmeh district, Idlib

Health status

February–December 2017

Clinical data analysis

Children and adolescents attending healthcare center in Atmeh district

Idlib

Not funded

Terkawi (2019) [93]

First: USA, Saudi Arabia

Last: Saudi Arabia

First: humanitarian, academic, clinical, thinktank/ research organization

Last: academic

Examines health status and barriers to accessing antenatal care among pregnant women in Northwestern Syria

Health system (service provision); health status; health determinants and risks

February–December 2017

Medical record review; cross-sectional survey

Pregnant women attending healthcare centers in Atmeh district for antenatal care

Idlib

Not funded

Vernier (2019) [94]

First: Syria

Last: UK

First: humanitarian

Last: humanitarian

Assesses health status and mortality among IDPs who recently arrived to Ein Issa camp in Al-Raqqa

Health status; mortality; humanitarian assessment, response or needs; health determinants and risks

November 2017

Cross-sectional survey

IDPs who had arrived at Ein Issa camp since October 2017

Al-Raqqa

MSF

Youssef (2019) [95]

First: Syria

Last: Lebanon

First: academic

Last: academic

Examines the epidemiology of visceral and cutaneous leishmaniases in Lattakia prior to and during the conflict

Health status

2008–2016

Registry data analysis

General population

Lattakia

The American Society of Tropical Medicine and Hygiene (ASTMH) assisted with the publication expenses

Ziveri (2019) [96]

First: Belgium

Last: Belgium

First: humanitarian

Last: independent

Examines impact of a psychosocial support program on the well-being and agency of Syrian farmers receiving livelihood support

Humanitarian assessment, response or needs

April–August 2017

Randomized control trial among Syrian farmers

Farming households from ten randomly selected villages who fulfilled inclusion criteria

Not reported

Not funded

  1. aThe other governorates are not specified
  2. b UOSSM Union of Medical Care and Relief Organizations
  3. c Violation Documentation Centre (VDC), Syrian Center for Statistics and Research (CSR-SY), Syrian Network for Human Rights (SNHR), and Syria Shuhada website (SS)
  4. d Unfunded, the study was self-funded. This research was supported by Damascus University
  5. e first published online in 2019, hence captured in this dataset
  6. f The governorate is not specified